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KMID : 0363220080460040547
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Korean Journal of Dermatology
2008 Volume.46 No. 4 p.547 ~ p.549
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A Case of Juvenile Xanthogranuloma Developed in a Neurofibromatosis Child with Family History
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Seo Hyun-Deok
Song Ji-Young
Chung Byoung-Soo
Choi Kyu-Cherl
Shin Bong-Seok
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Abstract
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Juvenile xanthogranuloma (JXG) is a fibrohistiocytic proliferative disorder predominant in infancy and childhood. It
is a benign and transient skin lesion that usually appears in the cephalic area. Recently, the concurrent finding of
neurofibromatosis (NF), juvenile chronic myelogenous leukemia (JCML), and JXG has been repeatedly reported. Especially, the family history of NF may represent a risk factor for the development of JCML in patients with NF and in patients with NF and JXG. So, a finding of JXG and NF in infants should alert the physician to a possible development of JCML. We report a case of JXG developed in a neurofibromatosis child with family history. (Korean J Dermatol 2008;46(4):547∼549)
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KEYWORD
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Juvenile chronic myelogenous Leukemia, Juvenile xanthogranuloma, Neurofibromatosis
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